There are two bugs in v0.4.11.6 which I consider to be severe enough to warrant a hotfix:
1. Attempting to assign a slave to some slave jobs will not work and cause a softlock.
2. Sometimes during sex the game will become unresponsive (I think this is only happening during anal sex but the same issue is potentially present in vaginal sex, spinneret sex, blowjobs and cunnilingus).
As such I will release a hotfix roughly 24 hours after this post.
EDIT: There is an additional major bug:
3. Personalities for all characters are wiped when loading a saved game.